Status: Closed
Activation Date: 2004JUL06
Closing Date: 2012MAY24
Phase: III
Description: A phase III study of the effect of re-irradiation for bone pain on urinary markers of osteoclast activity.
Eligibility: Patients with painful bone metasteses after previous palliative radiotherapy had been given to the diseased bone.
Objective: To correlate the response of re-irradiation to the change of urinary markers of osteoclast activity.
Participation: Patients randomized to SC.20 in selected centres in Canada and the United Kingdom.
Lay Description: The purpose of this study is to compare the response to radiation treatment to biochemical changes in urine.
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Hide Tissue Samples
| Disease Site | Trial Code | Patients Accrued | Patients - Blocks | Patients - Slides | Patients - Blocks and/or Slides |
| SYMPTOM CONTROL | SC20U | 169 | 0 | 0 | 0 |
(Core size is 0.6 mm)
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Fluid Samples| Disease Site | Trial Code | Patients Accrued | TMA Blocks | Patients on TMA Blocks |
| SYMPTOM CONTROL | SC20U | 169 | 0 | 0 |
| Disease Site | Trial Code | Patients Accrued | Patients - Whole Blood | Patients - Cellular Component of Blood | Patients - DNA extracted from Blood | Patients - RNA extracted from Blood | Patients - Plasma | Patients - Serum | Patients - Urine | Patients - Buccal |
| SYMPTOM CONTROL | SC20U | 169 | 0 | 0 | 0 | 0 | 0 | 0 | 58 | 0 |